What is it used for? Antabuse is used in the treatment of alcoholism. It helps to antabuse cost deter people from drinking alcohol. How does it work? Antabuse tablets contain the active ingredient disulfiram, which is a type of medicine called an aldehyde dehydrogenase inhibitor. It is prescribed to recovering alcoholics to help them abstain from drinking alcohol. If someone taking this medicine drinks alcohol, it quickly causes a severe, unpleasant and potentially dangerous reaction and knowledge of this fact can help to stop people from drinking. Advertisement - continue reading below, disulfiram works by interfering with the way the body metabolises alcohol. Alcohol is broken down in the body to a compound what does antabuse do called acetaldehyde. This how to get antabuse prescription is then normally broken down further by an enzyme in the liver called aldehyde dehydrogenase. Disulfiram stops this enzyme from working. This means that when alcohol what does antabuse do is consumed, the body can't process it normally. Instead, acetaldehyde builds up in the bloodstream. Most popular, high levels of acetaldehyde act directly on the heart and blood what does antabuse do vessels, causing flushing, a racing heartbeat and a drop in blood pressure that causes dizziness. Other unpleasant symptoms include a throbbing headache, shortness of breath, palpitations, nausea and vomiting. This reaction to alcohol is often called the disulfiram reaction and is usually what does antabuse do enough to deter people from having another drink. The disulfiram-alcohol reaction occurs within ten minutes of ingesting alcohol and may last for several hours. It can be potentially dangerous. For some people, knowing that they can't drink alcohol without having this reaction is what is needed to help them not give in to temptation in a weak moment. When starting this medicine you must not have drunk alcohol for at least 24 hours. You must not drink alcohol for two weeks after antabuse cost stopping the medicine, as the reaction may still occur in this time. It is important that disulfiram is used in combination with other forms of therapy and good social and psychological support to help you remain alcohol-free. How do I take it? Treatment with this medicine is usually started in a hospital metronidazole antabuse or specialised clinic. It is important to follow the instructions given by your what does antabuse do doctor regarding how many tablets to take.

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Antabus wiki

Uit Wikipedia, de vrije encyclopedie, ga naar: navigatie, zoeken, disulfiram (thiuramdisulfide) is een ontwenningsmiddel dat wordt gebruikt bij de behandeling van alcoholisme. Het zorgt ervoor antabus wiki dat de patint na antabus wiki alcoholinname geconfronteerd wordt met onaangename effecten zoals braken, hoofdpijn, versnelde hartslag, hevige transpiratie en rood aanlopen. Men heeft het gevoel doodziek te antabus wiki zijn. De werking van het middel is gebaseerd op de angst voor de zeer onaangename effecten na de inname van alcohol. Voor patinten met hartklachten zijn andere middelen beschikbaar omdat de hartslag zeer hoog kan antabus wiki oplopen bij het gebruik van disulfiram. Het voorschrijven van het middel is alleen zinvol als de verslaafde gemotiveerd is te stoppen met drinken en daarbij een extra steun antabus wiki in de rug wenst. Disulfiram is sinds 1948 1 internationaal op de markt. Het is op recept verkrijgbaar in tabletvorm onder de merknamen Antabus en Refusal. Om te ervaren hoe de werking is wordt soms na inname onder medische begeleiding een 'proefdronk' gedaan. Overigens wordt door veel ontwenningklinieken het middel niet of nauwelijks gebruikt. Veel verslavingsdeskundigen zijn van mening dat met het middel niet bereikt wordt dat men de drank op eigen kracht kan laten staan. Disulfiram kan bereid worden door oxidatie van natriumdi-ethyldithiocarbamaat met di-jood : ce 2 NaS2CN(C2H5)2 I2 - (C2H5)2NC(S)S-SC(S)N(C2H5)2 2 NaI. Dithiocarbamaat, overgenomen van " ". A disulfiram-like drug is a drug that causes hypersensitivity to the unpleasant and toxic effects of alcohol. 1 2, such effects may include nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover -like symptoms among others. 1 2, they are caused by accumulation of acetaldehyde, a major but toxic metabolite of alcohol formed by the enzyme alcohol dehydrogenase. 1 2, the reaction has been variously termed a disulfiram-like reaction, antabus wiki alcohol intolerance, and acetaldehyde syndrome. 3 The prototypical drug of this group is disulfiram (brand name Antabuse which acts as an acetaldehyde dehydrogenase inhibitor, preventing the metabolism of acetaldehyde into acetic acid, and is used in the treatment of alcoholism. 1 2 A variety of other drugs cause disulfiram-like reactions upon consumption of alcohol as unintended drug interactions and side effects. 1 2 Many disulfiram-like drugs act as inhibitors of acetaldehyde dehydrogenase similarly to disulfiram. However, some do not act via inhibition of this enzyme, and instead act via other, poorly elucidated mechanisms. Unlike acetaldehyde dehydrogenase inhibitors and other disulfiram-like drugs, alcohol dehydrogenase inhibitors such as fomepizole (brand name Antizol) inhibit the metabolism of alcohol into acetaldehyde, thereby increasing and extending the effects of alcohol and reducing its toxicity.

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